Introduction
Ibuprofen 400mg Tablets are a potent anti-inflammatory and analgesic medication used for short-term relief of moderate pain, inflammation, and fever. This strength is typically reserved for conditions that require stronger relief than lower-dose alternatives, such as toothache, menstrual cramps, muscle aches, joint pain, backache, and arthritis flare-ups.
Belonging to the NSAID (Non-Steroidal Anti-Inflammatory Drug) class, ibuprofen is a first-line treatment for many musculoskeletal and inflammatory disorders when used appropriately and under pharmacist or GP supervision.
How It Works
Ibuprofen works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for producing prostaglandins—chemical messengers that trigger inflammation, swelling, pain, and fever. By blocking this process, ibuprofen reduces both the sensation of pain and the biological signs of inflammation.
The 400mg strength offers a higher therapeutic dose per tablet compared to over-the-counter 200mg forms, often providing faster and longer-lasting relief for more intense or persistent symptoms.
Why Choose Ibuprofen 400mg Tablets
Effective for moderate to severe pain
Reduces inflammation and fever
Longer duration of action than 200mg tablets
Widely prescribed for arthritis, injury, and post-surgical recovery
Combines well with paracetamol for dual-analgesic effects
This strength is especially useful when lower-dose options are ineffective or when patients need extended relief without taking multiple tablets.
Important Note
Ibuprofen 400mg should only be taken under medical advice or supervision. It is not suitable for prolonged self-medication. Always follow dosage instructions carefully and take with food to reduce gastrointestinal risks.
Those with ulcers, bleeding disorders, asthma, cardiovascular issues, or renal impairment should consult their GP before use.



