Acetazolamide is a carbonic anhydrase inhibitor used as a diuretic to manage glaucoma, oedema (fluid retention), and acute altitude sickness. It works in the kidneys, eye, and brain to reduce fluid accumulation and pressure.
How It Works
By blocking the enzyme carbonic anhydrase, acetazolamide reduces bicarbonate reabsorption in the kidneys, increasing urine output and decreasing fluid overload. In the eye, it lowers intraocular pressure by reducing aqueous humour production. This makes it effective for glaucoma management and decreases brain fluid build-up associated with altitude sickness.
Why Choose Acetazolamide
It offers versatile use across multiple conditions—glaucoma, fluid retention, epilepsy adjunct, and altitude sickness—while having a quick onset of action. The tablet form allows easy daily dosing, and because it crosses the blood-brain barrier, it’s highly effective in neurological conditions like idiopathic intracranial hypertension.
Important Note
Ensure regular monitoring of kidney function, electrolytes (especially potassium), and blood pH for long-term use. Do not use if allergic to sulfonamides or with severe kidney or liver disease. Stay well hydrated, especially with higher doses, and avoid strenuous activity in extreme heat to prevent dehydration.
